Tri-Luma (Fluocinolone + Hydroquinone + Tretinoin): Top Prescription for Melasma in 2025 Tri-Luma Cream has become a gold-standard prescription formula for treating melasma, a stubborn form of hyperpigmentation triggered by hormones, sun exposure, or genetics. With its triple-action blend of fluocinolone acetonide (0.01%), hydroquinone (4%), and tretinoin (0.05%), Tri-Luma targets melanin at every level of […]